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Diagn Microbiol Infect Dis. 2012 Oct;74(2):186-9. doi: 10.1016/j.diagmicrobio.2012.06.015. Epub 2012 Aug 2.

Prototheca wickerhamii as a cause of neuroinfection in a child with congenital hydrocephalus. First case of human protothecosis in Poland.

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Department of Clinical Microbiology, Children's University Hospital of Kraków, Kraków, Poland.


This report describes a rare case of neuroinfection due to Prototheca wickerhamii in a child with severe, congenital hydrocephalus. The infection resolved completely after the patient was treated with oral ketoconazole, followed by intravenous fluconazole and amphotericin B. A probable source of infection was contamination during ventriculoperitoneal drain care procedures.

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