Format

Send to

Choose Destination
Antimicrob Agents Chemother. 1990 Sep;34(9):1824-6.

Magainin analogs effective against pathogenic protozoa.

Author information

1
Department of Pathology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 19107.

Abstract

The in vitro activities of magainin analogs against Blastocystis hominis, Entamoeba histolytica, and Trypanosoma cruzi were assessed by protozoan morphological integrity and motility. The antiprotozoan activities in descending order were magainin B greater than G greater than H, the same order as the alpha-helix contents of the analogs. Magainin B and G were effective against B. hominis, T. cruzi, and E. histolytica.

PMID:
2285300
PMCID:
PMC171939
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for HighWire Icon for PubMed Central
Loading ...
Support Center