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Items: 7


β-TrCP-mediated IRAK1 degradation releases TAK1-TRAF6 from the membrane to the cytosol for TAK1-dependent NF-κB activation.

Cui W, Xiao N, Xiao H, Zhou H, Yu M, Gu J, Li X.

Mol Cell Biol. 2012 Oct;32(19):3990-4000. doi: 10.1128/MCB.00722-12. Epub 2012 Jul 30.


Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics.

Bennett EJ, Rush J, Gygi SP, Harper JW.

Cell. 2010 Dec 10;143(6):951-65. doi: 10.1016/j.cell.2010.11.017.


Defining the human deubiquitinating enzyme interaction landscape.

Sowa ME, Bennett EJ, Gygi SP, Harper JW.

Cell. 2009 Jul 23;138(2):389-403. doi: 10.1016/j.cell.2009.04.042. Epub 2009 Jul 16.


betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis.

Dehan E, Bassermann F, Guardavaccaro D, Vasiliver-Shamis G, Cohen M, Lowes KN, Dustin M, Huang DC, Taunton J, Pagano M.

Mol Cell. 2009 Jan 16;33(1):109-16. doi: 10.1016/j.molcel.2008.12.020.


Homodimer of two F-box proteins betaTrCP1 or betaTrCP2 binds to IkappaBalpha for signal-dependent ubiquitination.

Suzuki H, Chiba T, Suzuki T, Fujita T, Ikenoue T, Omata M, Furuichi K, Shikama H, Tanaka K.

J Biol Chem. 2000 Jan 28;275(4):2877-84.


Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha.

Tan P, Fuchs SY, Chen A, Wu K, Gomez C, Ronai Z, Pan ZQ.

Mol Cell. 1999 Apr;3(4):527-33.

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