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Acta Paediatr Jpn. 1990 Oct;32(5):571-4.

Neonatal tuberous sclerosis with heart and brain tumors.

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Department of Pediatrics, Jikei University School of Medicine, Tokyo, Japan.


A 6-day-old neonate with tuberous sclerosis having brain and cardiac tumors is reported. The patient presented with a seizure 20 minutes after birth. Cranial ultrasonography and computed tomography on admission showed a large and round high-density tumor lesion in the left frontal lobe. Echocardiography also showed a large tumor lesion beside the left ventricle wall, and a diagnosis of tuberous sclerosis was promptly made. Two months later, a periventricular calcified lesion was found on the demonstrated portion, and the tumor lesion initially observed in the brain had disappeared. These findings suggest that the initial tumor lesion found in the brain developed into a typical calcified lesion.

[Indexed for MEDLINE]

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