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Analyst. 2012 Sep 21;137(18):4119-22. doi: 10.1039/c2an35640f. Epub 2012 Jul 30.

Label-free molecular analysis of live Neospora caninum tachyzoites in host cells by selective scanning Raman micro-spectroscopy.

Author information

1
School of Physics and Astronomy, University of Nottingham, UK.

Abstract

A selective scanning method was used to measure spatially resolved Raman spectra of live Neospora caninum tachyzoites colonizing human brain microvascular-endothelial cells. The technique allowed the detection of nucleic acids, lipids and proteins linked to the parasites and their cellular micro-environment at ∼10× shorter acquisition time compared to raster scanning.

PMID:
22842554
DOI:
10.1039/c2an35640f
[Indexed for MEDLINE]

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