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Microbes Infect. 2012 Nov;14(13):1211-9. doi: 10.1016/j.micinf.2012.07.001. Epub 2012 Jul 25.

Mycobacterium tuberculosis modulators of the macrophage's cellular events.

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1
Division of Infectious Diseases, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.

Abstract

A number of mycobacterial macromolecules have been shown to target biological processes within host macrophages; however, the exact mechanism for the majority of these host-pathogen interactions is poorly understood. The following review summarizes current knowledge and expands on a subset of mycobacterial effectors for which a cognate substrate, cellular partner or signaling pathway have been experimentally identified within the human host.

PMID:
22841679
DOI:
10.1016/j.micinf.2012.07.001
[Indexed for MEDLINE]
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