Hypertrophic donavanosis in a young pregnant woman

C A Liverani; D Lattuada; S Mangano; C Pignatari; D Puglia; E Monti; G Bolis

doi:10.1016/j.jpag.2011.10.002

Hypertrophic donavanosis in a young pregnant woman

J Pediatr Adolesc Gynecol. 2012 Aug;25(4):e81-3. doi: 10.1016/j.jpag.2011.10.002.

Authors

C A Liverani¹, D Lattuada, S Mangano, C Pignatari, D Puglia, E Monti, G Bolis

Affiliation

¹ Department of Mother and Infant Sciences, University of Milan, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

PMID: 22840941
DOI: 10.1016/j.jpag.2011.10.002

Abstract

Background: Donovanosis is a chronic bacterial illness, progressive and indolent, which normally attacks the skin and mucous membranes in the genital and perigenital regions.

Case: An 18-year-old pregnant female presented with large, hypertrophic lesions in the ano-genital region. HIV serology was negative. Pap smear revealed a CIN 1 associated with HPV infection. Biopsy yielded macrophages laden with Gram-negative Donovan bodies.

Summary and conclusion: A diagnosis of vulvar and perianal donovanosis was reached; the patient decided to terminate the pregnancy and was treated with azithromycin, which led to clinical resolution.

Publication types

Case Reports

MeSH terms

Abortion, Induced
Adolescent
Anus Diseases / microbiology
Female
Granuloma Inguinale / diagnosis*
Humans
Pregnancy
Pregnancy Complications, Infectious / diagnosis*
Vulvar Diseases / microbiology