Send to

Choose Destination
Eur J Mass Spectrom (Chichester). 2012;18(3):301-12. doi: 10.1255/ejms.1187.

Artifacts in amine analysis from anodic oxidation of organic solvents upon electrospray ionization for mass spectrometry.

Author information

Institute of Analytical Chemistry, University of Leipzig, Germany.


Different phenylenediamines were used to explore anodic oxidation in solution during electrospray ionization (ESI) mass spectrometry analysis. In our experiments, a series of unknown ionic species was detected in the phenylenediamine solutions. Our results propose that reactions of phenylenediamines with species formed by anodic oxidation of typical ESI solvents during the electrospray ionization process such as formaldehyde are producing these peaks. Identification of these compounds inter alia suggests formal alkylation, a reaction not reported so far as a result of electrolytic oxidation in the prospective organic solvents.


Supplemental Content

Full text links

Icon for Atypon
Loading ...
Support Center