Constructs and scaffolds employed to regenerate dental tissue

Dent Clin North Am. 2012 Jul;56(3):577-88. doi: 10.1016/j.cden.2012.05.008.

Abstract

Dental tissue injury and regeneration affects the daily lives of almost everyone. Tissue engineering is emerging as a promising therapy to regenerate missing teeth and dental tissues. The aim of regenerative dental therapies is to restore patients to full oral health. This means restoring normal function to missing or damaged tissue. Regeneration approaches use a combination of scaffolds, stem cells, growth factors, tissue engineering, organ tissue culture, transplantation, and tissue grafting. There are 8 key elements to create and use tissue constructs for tissue regeneration. These will be described in detail in this article.

Publication types

  • Review

MeSH terms

  • Biocompatible Materials
  • Cell Movement
  • Extracellular Matrix Proteins / metabolism
  • Extracellular Matrix Proteins / therapeutic use*
  • Guided Tissue Regeneration, Periodontal / methods*
  • Humans
  • Intercellular Signaling Peptides and Proteins / therapeutic use
  • Stem Cell Transplantation / methods*
  • Tissue Scaffolds*
  • Tooth / physiopathology*

Substances

  • Biocompatible Materials
  • Extracellular Matrix Proteins
  • Intercellular Signaling Peptides and Proteins