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Oxid Med Cell Longev. 2012;2012:805762. doi: 10.1155/2012/805762. Epub 2012 Jul 5.

Wine polyphenols: potential agents in neuroprotection.

Author information

1
GESVAB, ISVV, Université de Bordeaux, France.

Abstract

There are numerous studies indicating that a moderate consumption of red wine provides certain health benefits, such as the protection against neurodegenerative diseases. This protective effect is most likely due to the presence of phenolic compounds in wine. Wine polyphenolic compounds are well known for the antioxidant properties. Oxidative stress is involved in many forms of cellular and molecular deterioration. This damage can lead to cell death and various neurodegenerative disorders, such as Parkinson's or Alzheimer's diseases. Extensive investigations have been undertaken to determine the neuroprotective effects of wine-related polyphenols. In this review we present the neuroprotective abilities of the major classes of wine-related polyphenols.

PMID:
22829964
PMCID:
PMC3399511
DOI:
10.1155/2012/805762
[Indexed for MEDLINE]
Free PMC Article
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