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J Chem Biol. 2012 Jan;5(1):5-17. doi: 10.1007/s12154-011-0064-8. Epub 2011 Jul 24.

Shikimic acid: review of its analytical, isolation, and purification techniques from plant and microbial sources.

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Institute for Problems of Chemical and Energetic Technologies, Siberian Branch of the Russian Academy of Sciences (IPCET SB RAS), ul. Socialisticheskaya, 1, Biysk, 659322 Russia.


Shikimic acid properties and its available analytical techniques are discussed. Plants having the highest content of shikimic acid are shown. The existing isolation methods are analyzed and the most optimal approaches to extracting this acid from natural sources (plants and microorganisms) are considered.


Dehydroshikimate; Hyperproducing strain; Oseltamivir; Shikimate dehydrogenase; Shikimate pathway; Shikimic acid

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