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Cancer Radiother. 2012 Jul-Aug;16(4):315-21. doi: 10.1016/j.canrad.2012.05.006. Epub 2012 Jul 19.

[Claudius Regaud (1870-1940): A pioneer of radiobiology and radiotherapy].

[Article in French]

Author information

1
CR-U, groupe de radiobiologie, centre de recherche en cancérologie de Lyon, Institut national de la santé et de la recherche médicale, Lyon, France. Nicolas.foray@inserm.fr

Abstract

Born in 1870, Claudius Regaud was a pioneer of radiobiology and radiotherapy. As histologist, he developed a new staining technique that allowed him to describe in detail all the reproduction system of a number of animal models. As radiobiologist, he contradicted the interpretations of Tribondeau and Bergonié about relationships between cell proliferation and radiosensitivity. In 1908, he suggested that chromatin was the main target of radiation. As physician, he defined the first bases of anti-cancer radiation treatments and treated patients suffering from incurable cancer from 1911. As military doctor, he organized war hospitals by creating multidisciplinary teams for the surgery of hurts. Organizer, he was one of the founders of the League against Cancer. As radiotherapist and brachytherapist, he contributed to make Institut Curie an international reference center for research and teaching, with nearly a thousand treated patients. As globe-trotter, he was at the origin of the creation of numerous worldwide radiotherapy and radiobiology centers. He died in December 1940 and let an impressive but still misknown scientific heritage. A re-reading of the familial archives and the Regaud Fund of Institut Curie is the occasion to remind the contribution of Regaud.

PMID:
22818408
DOI:
10.1016/j.canrad.2012.05.006
[Indexed for MEDLINE]

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