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Mens Sana Monogr. 2004 Jan;2(1):45-51.

What shall we do about our concern with the most recent in psychiatric research?

Abstract

Most clinicians and researchers are concerned with recent advances in psychiatry. This involves the danger whether something time-tested may get sidelined for extra-scientific reasons. That the pharmaceutical industry and superspecialist researcher may keep churning out new findings to impress audiences is only a partial truth. Research progresses by refutation and self-correction. Acceptance in science is always provisional; changing paradigms, frameworks of enquiry and raising new questions is integral to break through in scientific knowledge. Hence, there is in science a constant concern with the new. Moreover, the number of treatment non- responders to the time-tested swells with time, and researchers feel challenged to find ways and means of resolving their difficulties. Newer challenges need newer strategies. Obsession with the most recent can lead us astray, but a healthy evidence-based acceptance of the new is essential for advancement in psychiatric research. As indeed of research in all fields of medicine. And of science in general. The role of lithium and newer mood stabilizers in bipolar disorders are taken as examples to highlight this point.

KEYWORDS:

Bipolar Disorders; Lithium; Mood-stabilizers; Paradigm shift; Pharmaceutical Industry; Psychiatric research; Refutation; Treatment non-responders

PMID:
22815604
PMCID:
PMC3400305
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