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Lab Chip. 2012 Nov 21;12(22):4605-9. doi: 10.1039/c2lc40563f.

Single-cell electroporation using a multifunctional pipette.

Author information

1
Department of Chemical and Biological Engineering, Chalmers University of Technology, S-41296 Göteborg, Sweden.

Abstract

We present here a novel platform combination, using a multifunctional pipette to individually electroporate single-cells and to locally deliver an analyte, while in their culture environment. We demonstrate a method to fabricate low-resistance metallic electrodes into a PDMS pipette, followed by characterization of its effectiveness, benefits and limits in comparison with an external carbon microelectrode.

PMID:
22810424
PMCID:
PMC3805499
DOI:
10.1039/c2lc40563f
[Indexed for MEDLINE]
Free PMC Article

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