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Crit Care. 2012 Jul 19;16(4):227. doi: 10.1186/cc11242.

Pro/con debate: Is etomidate safe in hemodynamically unstable critically ill patients?

Abstract

Etomidate is an induction agent known for its smooth intubating conditions and cardiovascular stability. Studies, however, have shown that a single dose of etomidate can result in a prolonged adrenal insufficiency. The impact of this in patients with sepsis has been a matter for debate. This review presents a pro/con case for using etomidate in hemodynamically unstable critically ill patients and provides guidance for alternative induction techniques and when the use of etomidate might be justified despite these concerns.

PMID:
22809235
PMCID:
PMC3580672
DOI:
10.1186/cc11242
[Indexed for MEDLINE]
Free PMC Article
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