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J Surg Oncol. 2012 Oct 1;106(5):595-9. doi: 10.1002/jso.23207. Epub 2012 Jul 17.

Adrenal insufficiency.

Author information

1
Department of Endocrinology, Diabetes, Metabolism, Cleveland Clinic, Cleveland, Ohio 44195, USA.

Abstract

Adrenocortical insufficiency may arise through primary failure of the adrenal glands or due to lack of ACTH stimulation as a result of pituitary or hypothalamic dysfunction. Prolonged administration of exogenous steroids will suppress the hypothalamic-pituitary-adrenal axis, and hence cortisol secretion. We review briefly the causes, investigation, and treatment of adrenal insufficiency, and highlight aspects of particular relevance to patients with adrenal tumors.

PMID:
22806629
DOI:
10.1002/jso.23207
[Indexed for MEDLINE]

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