Format

Send to

Choose Destination
J Comput Assist Tomogr. 2012 Jul-Aug;36(4):381-7. doi: 10.1097/RCT.0b013e318256b1ba.

Qualitative assessment of enhancement in a renal mass: contribution of subtraction CT.

Author information

1
Division of Abdominal Imaging and Intervention, Department of Imaging, Massachusetts General Hospital, Boston, MA 02114, USA.

Abstract

PURPOSE:

To evaluate the impact of subtraction CT on reader confidence and diagnostic accuracy when characterizing renal masses.

MATERIALS AND METHODS:

In this institutional review board-approved retrospective study, 159 patients (85 men and 74 women; mean age, 62.6 years; range, 22-88 years) underwent routine unenhanced and contrast-enhanced multidetector computed tomography (MDCT) for renal lesion characterization. Subtraction images were subsequently generated on scanner console. Two readers independently reviewed the MDCT images to characterize presence of enhancement using a 6-point scale during 3 blinded review sessions of (1) only subtraction, (2) routine, and (3) combined subtraction and routine images. The standard of reference consisted of either histopathology or follow-up imaging and clinical data.

RESULTS:

Of the 240 lesions evaluated, 60 lesions (mean, 3.2 cm; range, 1-7.5 cm) were enhancing and 180 lesions (mean, 2.7 cm; range, 0.5-12 cm) were nonenhancing. For determination of lesion enhancement, a combined evaluation of routine MDCT and subtraction images improved reader confidence in 60% to 63% of lesions (P < 0.001). The combined evaluation also provided the highest sensitivity (97%), specificity (99%), and accuracy (98.9%).

CONCLUSION:

When used in combination with routine image interpretation, subtraction CT improves reader confidence and diagnostic accuracy in identifying enhancement in renal lesions.

PMID:
22805664
DOI:
10.1097/RCT.0b013e318256b1ba
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wolters Kluwer
Loading ...
Support Center