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Int J Clin Pract. 2012 Sep;66(9):897-905. doi: 10.1111/j.1742-1241.2012.02992.x. Epub 2012 Jul 16.

Structured management strategy based on the Gastro-oesophageal Reflux Disease (GERD) Questionnaire (GerdQ) vs. usual primary care for GERD: pooled analysis of five cluster-randomised European studies.

Author information

1
Digestive Functional Disorders Unit, Hospital Universitario La Fe, Valencia, Spain. jponceg@medynet.com

Abstract

BACKGROUND:

Response to treatment among primary care patients with gastro-oesophageal disease (GERD) is variable.

AIM:

The GERD Management Project (GMP) evaluated the effectiveness of a structured management approach to GERD vs. standard treatment (usual care).

METHODS:

Data from five cluster-randomised clinical trials in adult primary care patients with symptoms of GERD were pooled. The structured pathway was based on the self-administered GERD Questionnaire (GerdQ) and was compared with standard treatment.

RESULTS:

1734 patients were enrolled (structured treatment, n=834; standard treatment, n=900). The difference in the mean GerdQ score change from baseline favoured the structured pathway (-0.61; 95% CI: -0.88, -0.34; p<0.001). The odds ratio for an indication for treatment revision at the end of follow-up (structured vs. standard treatment) was 0.39 (95% CI: 0.29, 0.52; p=0.001).

CONCLUSIONS:

Management of primary care patients with GERD can be improved by systematic stratification of patients using a patient management tool such as the GerdQ.

PMID:
22805293
PMCID:
PMC3601421
DOI:
10.1111/j.1742-1241.2012.02992.x
[Indexed for MEDLINE]
Free PMC Article

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