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Am J Trop Med Hyg. 2012 Sep;87(3):576-8. doi: 10.4269/ajtmh.2012.11-0416. Epub 2012 Jul 16.

Detection of Nipah virus RNA in fruit bat (Pteropus giganteus) from India.

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1
Microbial Containment Complex, National Institute of Virology, Pune, India.

Abstract

The study deals with the survey of different bat populations (Pteropus giganteus, Cynopterus sphinx, and Megaderma lyra) in India for highly pathogenic Nipah virus (NiV), Reston Ebola virus, and Marburg virus. Bats (n = 140) from two states in India (Maharashtra and West Bengal) were tested for IgG (serum samples) against these viruses and for virus RNAs. Only NiV RNA was detected in a liver homogenate of P. giganteus captured in Myanaguri, West Bengal. Partial sequence analysis of nucleocapsid, glycoprotein, fusion, and phosphoprotein genes showed similarity with the NiV sequences from earlier outbreaks in India. A serum sample of this bat was also positive by enzyme-linked immunosorbent assay for NiV-specific IgG. This is the first report on confirmation of Nipah viral RNA in Pteropus bat from India and suggests the possible role of this species in transmission of NiV in India.

PMID:
22802440
PMCID:
PMC3435367
DOI:
10.4269/ajtmh.2012.11-0416
[Indexed for MEDLINE]
Free PMC Article
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