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Chem Commun (Camb). 2012 Aug 28;48(67):8335-7. doi: 10.1039/c2cc33016d. Epub 2012 Jul 16.

Chemical speciation of nanoparticles surrounding metal-on-metal hips.

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1
Department of Materials, Imperial College London, London, UK.

Abstract

Spectromicroscopy of tissue surrounding failed CoCr metal-on-metal hip replacements detected corroded nanoscale debris in periprosthetic tissue in two chemical states, with concomitant mitochondrial damage. The majority of debris contained Cr(3+), with trace amounts of oxidised cobalt. A minority phase containing a core of metallic chromium and cobalt was also observed.

PMID:
22801350
DOI:
10.1039/c2cc33016d
[Indexed for MEDLINE]
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