Format

Send to

Choose Destination
Prog Neurobiol. 2012 Nov;99(2):106-16. doi: 10.1016/j.pneurobio.2012.07.003. Epub 2012 Jul 16.

Physiological reactivity to psychological stress in human pregnancy: current knowledge and future directions.

Author information

1
Department of Psychiatry, The Ohio State University Medical Center, Columbus, OH 43210, USA. lisa.christian@osumc.edu

Abstract

Cardiovascular and neuroendocrine reactivity to acute stress are important predictors of health outcomes in non-pregnant populations. Greater magnitude and duration of physiological responses have been associated with increased risk of hypertensive disorders and diabetes, greater susceptibility to infectious illnesses, suppression of cell-mediated immunity as well as risk for depression and anxiety disorders. Stress reactivity during pregnancy has unique implications for maternal health, birth outcomes, and fetal development. However, as compared to the larger literature, our understanding of the predictors and consequences of exaggerated stress reactivity in pregnancy is limited. This paper reviews the current state of this literature with an emphasis on gaps in knowledge and future directions.

PMID:
22800930
PMCID:
PMC3479316
DOI:
10.1016/j.pneurobio.2012.07.003
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center