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Am Heart J. 2012 Jul;164(1):66-71.e1. doi: 10.1016/j.ahj.2012.03.020. Epub 2012 Jun 13.

Prevalence of Takotsubo cardiomyopathy in the United States.

Author information

1
University of Arkansas for Medical Sciences, Little Rock, USA. AJDeshmukh@uams.edu

Abstract

BACKGROUND:

The aim of this study was to describe the prevalence of Takotsubo cardiomyopathy (TTC), age-gender interaction, and various comorbidities associated with it based on nationwide hospitalization records. Takotsubo cardiomyopathy is an increasingly reported clinical syndrome; however, there are no data on its prevalence in the general US population.

METHODS:

The Nationwide Inpatient Sample discharge records were queried for the year 2008 using the International Classification of Diseases, Ninth Revision, code 429.83.

RESULTS:

There were 6,837 patients diagnosed with TTC among 33,506,402 hospitalizations in the Nationwide Inpatient Sample database. Women were found to have higher odds of developing TTC (odds ratio 8.8). Women >55 years old had 4.8 times higher odds for developing TTC when compared with women <55 years old. Smoking, alcohol abuse, anxiety states, and hyperlipidemia were commonly associated with TTC. The peak incidence of hospitalization for TTC was in summer.

CONCLUSION:

Takotsubo cardiomyopathy was diagnosed in about 0.02% of all hospitalizations in the United States, mostly in elderly women with history of smoking, alcohol abuse, anxiety states, and hyperlipidemia.

PMID:
22795284
DOI:
10.1016/j.ahj.2012.03.020
[Indexed for MEDLINE]
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