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Med Clin North Am. 2012 Jul;96(4):699-711. doi: 10.1016/j.mcna.2012.02.006. Epub 2012 Mar 6.

Genes and chronic obstructive pulmonary disease.

Author information

1
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Morehouse School of Medicine, Atlanta, GA 30310-1495, USA.

Abstract

Although much remains to be done, recent advances and the advent of new methodologies are promising and should yield increased understanding of the genetic and epigenetic mechanisms influencing the pathogenesis of COPD, both related and unrelated to severe AAT deficiency. Such understanding should ultimately be translated into novel approaches to prevent, diagnose, and treat COPD.

PMID:
22793939
PMCID:
PMC3399759
DOI:
10.1016/j.mcna.2012.02.006
[Indexed for MEDLINE]
Free PMC Article

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