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Chem Commun (Camb). 2012 Aug 28;48(67):8332-4. doi: 10.1039/c2cc33913g. Epub 2012 Jul 13.

Microbubble-sonosensitiser conjugates as therapeutics in sonodynamic therapy.

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1
Sonidel Ltd., Dublin 5, Republic of Ireland.

Abstract

A Rose Bengal sonosensitiser has been covalently attached to a lipid microbubble and the resulting conjugate shown to produce higher levels of singlet oxygen, enhanced cytotoxicity in a cancer cell line and a greater reduction in tumour growth than the sonosensitiser alone.

PMID:
22790600
DOI:
10.1039/c2cc33913g
[Indexed for MEDLINE]
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