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Curr Biol. 2012 Jul 10;22(13):R522-5. doi: 10.1016/j.cub.2012.05.037.

Cancer and inflammation: an aspirin a day keeps the cancer at bay.

Author information

1
Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, Karlsruhe, Germany. Maria.Mione@kit.edu

Abstract

Live imaging of the interactions between oncogene-transformed cells and leukocytes in zebrafish reveals that PGE(2) promotes the survival and proliferation of cancer cells. Non-steroid anti-inflammatory drugs, like aspirin, are the effective inhibitors of PGE(2) production and could be used with other anti-tumor agents in the treatment of cancer.

PMID:
22789999
PMCID:
PMC6022370
DOI:
10.1016/j.cub.2012.05.037
[Indexed for MEDLINE]
Free PMC Article

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