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Complement Ther Clin Pract. 2012 Aug;18(3):182-9. doi: 10.1016/j.ctcp.2012.03.002. Epub 2012 May 3.

A randomised controlled pilot feasibility study of the physical and psychological effects of an integrated support programme in breast cancer.

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  • 1The Haven, Effie Road, London SW6 1TB, UK.


A pilot study was conducted to assess recruitment and effectiveness of an integrated support programme in women with breast cancer. Twelve participants were randomised to receive medical care with or without the support programme. Psychosocial questionnaires and immune/hormonal assays were completed at baseline, three and six months. Recruitment was problematic. In the intervention group, mental fatigue was significantly improved (p = 0.016) compared to controls; increased NK cell activity suggested an improvement in immune function. Total stress (p = 0.009), anxiety (p = 0.032) and endocrine-specific (p = 0.032) symptoms were significantly improved in the controls. A large-scale randomisation trial appears warranted, dependent upon effective recruitment.

Copyright © 2012 Elsevier Ltd. All rights reserved.

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