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Auris Nasus Larynx. 1990;17(3):173-80.

Inner ear impairment following combined CDDP (platinum preparation) and radiation therapy.

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Department of Otolaryngology, Fukushima Medical College, Japan.


Hearing ability was examined in patients with head and neck cancer treated by combined CDDP and electron beam therapy. In 3 of 7 patients with maxillary cancer, hearing impairment apparently attributable to the therapy was noted on the affected side. In one of these 3 patients, the temporal bone was observed, but the cause of hearing impairment could not be determined. We present patients with cancer of the external ear in whom radiation-caused hearing impairment worsened probably due to combined CDDP and electron beam therapy.

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