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Chembiochem. 2012 Jul 23;13(11):1564-8. doi: 10.1002/cbic.201200334. Epub 2012 Jul 6.

Genetically targetable and color-switching fluorescent probe.

Author information

1
Molecular Biosensor and Imaging Center, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, PA 15213, USA. ydmytry@gmail.com

Abstract

Color bind: We have developed a probe TMR-para-MG that switches its fluorescence emission upon binding to a fluorogen-activating protein (FAP). In cells that express FAP, this dye labels target sites in one color and mitochondria in another color, thus it might be a suitable tool for monitoring changes in mitochondrial membrane potential.

PMID:
22777954
PMCID:
PMC3517117
DOI:
10.1002/cbic.201200334
[Indexed for MEDLINE]
Free PMC Article
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