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Nat Rev Genet. 2012 Jul 10;13(8):589-94. doi: 10.1038/nrg3290.

The place of genetics in ageing research.

Author information

1
Albert Einstein College of Medicine, 1300 Morris Park Avenue, Belfer Building, #701, Bronx, New York City, New York 10461, USA. nir.barzilai@einstein.yu.edu

Abstract

Rapidly increasing numbers of older people present many countries with growing social and economic challenges. Yet despite the far-reaching implications of ageing, its biological basis remains a topic of much debate. Recent advances in genomics have spurred research on ageing and lifespan in human populations, adding to extensive genetic studies being carried out in model organisms. But how far is ageing controlled by our genes? In this Viewpoint, six experts present their opinions and comment on future directions in ageing research.

PMID:
22777128
DOI:
10.1038/nrg3290
[Indexed for MEDLINE]

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