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Hum Vaccin Immunother. 2012 Jul;8(7):1010-2. doi: 10.4161/hv.20805. Epub 2012 Jul 1.

Accelerated vaccine development against emerging infectious diseases.

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Vaccine and Immunotherapy Center, Infectious Diseases Medicine, Massachusetts General Hospital, Charlestown, MA, USA.


Emerging and re-emerging infectious diseases represent a major challenge to vaccine development since it involves two seemingly contradictory requirements. Rapid and flexible vaccine generation while using technologies and processes that can facilitate accelerated regulatory review. Development in the "-omics" in combination with advances in vaccinology offer novel opportunities to meet these requirements. Here we describe how a consortium of five different organizations from academia and industry is addressing these challenges. This novel approach has the potential to become the new standard in vaccine development allowing timely deployment to avert potential pandemics.

[Indexed for MEDLINE]

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