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J Neuropsychiatry Clin Neurosci. 2012 Spring;24(2):241-6. doi: 10.1176/appi.neuropsych.11090207.

New-onset psychosis associated with dandy-walker variant in an adolescent female patient.

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Department of Psychiatry and Behavioral Sciences, University of Miami, Miami, FL, USA.


The relationship between psychotic disorders, in particular, schizophrenia, and neurodevelopmental abnormalities has been conceptualized in the latest literature. Dandy-Walker variant, defined by cystic dilatation of the fourth ventricle and hypoplasia of the inferior portion of the vermis without enlargement of the posterior fossa, is a distinctive entity believed to represent a mild subtype of Dandy-Walker complex. The authors hypothesize a correlation between new onset of psychosis and cerebellar abnormalities in an adolescent patient.

[Indexed for MEDLINE]

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