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Infect Dis Clin North Am. 1990 Dec;4(4):731-46.

Spirochetal infection of the central nervous system.

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Health Sciences Center, State University, New York, Stony Brook.


Four spirochetal diseases frequently involve the central nervous system: syphilis, leptospirosis, relapsing fever, and Lyme borreliosis. In particular, syphilis and Lyme borreliosis are increasing problems. During the spirochetemic phase there is seeding of the nervous system. After a quiescent latent period, there may be late disease flareups producing a variety of neurologic syndromes. Cerebrospinal fluid examination is very helpful in these infections.

[Indexed for MEDLINE]

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