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Indian J Pathol Microbiol. 2012 Apr-Jun;55(2):245-7. doi: 10.4103/0377-4929.97895.

Clear cell adenocarcinoma of the male urethral tract.

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Department of Pathology, Rajiv Gandhi Cancer Institute and Research Centre, Rohini, Delhi, India.


We present a rare case of clear cell adenocarcinoma of the male bulbomembranous urethra. Mostly these tumors have been described in the female urethral tract with its possible origin from mullerian remnants, wolffian remnants or paraurethral glands. Histologically, these tumors have typically tubulocystic pattern comprising of hobnailed cells with clear glycogenated cytoplasm along with well-defined cytoplasmic membranes. This case is being presented due to its rarity, aggressive behavior and to discuss, trauma as its possible etiological factor.

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