Format

Send to

Choose Destination
Cell Metab. 2012 Jul 3;16(1):6-8. doi: 10.1016/j.cmet.2012.06.010.

Caloric restriction in mTORC1 control of intestinal homeostasis.

Abstract

Reducing caloric intake, while maintaining adequate nutrition, promotes longevity in diverse organisms, possibly by preserving stem and progenitor cell function. Yilmaz and colleagues (2012) now show that caloric restriction alters intestinal stem cell proliferation and differentiation, and elucidate a mechanism for how the mammalian stem cell niche responds to environmental inputs.

PMID:
22768834
DOI:
10.1016/j.cmet.2012.06.010
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center