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Adolesc Med State Art Rev. 2012 Apr;23(1):192-206, xii-xiii.

Human papillomavirus disease in adolescents: management and prevention.

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Division of Adolescent Medicine, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Ave., Cincinnati, Ohio 45229, USA.


Human papillomaviruses (HPV) are a family of viruses that infect the epithelium of many parts of the body. Persistent infection with high-risk HPV is necessary but insufficient to cause cervical cancer. High-risk HPV types are increasingly recognized as a risk factor for cancers other than cervical cancer. A large proportion of vulvar, vaginal, anal, penile, and oropharyngeal cancers are associated with HPV. Low-risk HPV types cause genital warts. Recent advancement in the prevention of HPV infection, genital warts, and HPV-associated precancers and cancers include vaccination. Until the full potential of vaccination can be attained, cervical cancer screening remains an important component of prevention.

[Indexed for MEDLINE]

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