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World J Radiol. 2012 May 28;4(5):236-40. doi: 10.4329/wjr.v4.i5.236.

Reactivation of tuberculosis in hepatocellular carcinoma treated with transcatheter arterial chemoembolization: A report of 3 cases.

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Yun Jeung Kim, Pyung Gohn Goh, Hee Seok Moon, Eaum Seok Lee, Seok Hyun Kim, Byung Seok Lee, Heon Young Lee, Division of Hepatology, Department of Internal Medicine, Chung-Nam National University Hospital, 640 Daesa-Dong, Jung-Gu, Daejeon 301-721, South Korea.


Pulmonary tuberculosis is an opportunistic infection that can be reactivated in immunocompromised conditions, for example, in malignancy or after liver transplantation. Hepatocellular carcinoma (HCC) has a high mortality rate because it is frequently diagnosed at an advanced stage. Although surgical resection is the established curative measure for HCC, it is only feasible for early-stage HCC. Transcatheter arterial chemoembolization (TACE) is the most common treatment modality for patients with unresectable HCC. However, repeated TACE sessions and, occasionally, the tumor itself can further impair the reserve hepatic function and immunity. We report 3 recent cases of HCC with reactivation of pulmonary tuberculosis after TACE.


Hepatocellular carcinoma; Reactivation; Transcatheter arterial chemoembolization; Tuberculosis

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