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Cytoskeleton (Hoboken). 2012 Oct;69(10):700-9. doi: 10.1002/cm.21045. Epub 2012 Jul 3.

Cytokinesis mechanics and mechanosensing.

Author information

1
Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Abstract

Cytokinesis shape change occurs through the interfacing of three modules, cell mechanics, myosin II-mediated contractile stress generation and sensing, and a control system of regulatory proteins, which together ensure flexibility and robustness. This integrated system then defines the stereotypical shape changes of successful cytokinesis, which occurs under a diversity of mechanical contexts and environmental conditions.

PMID:
22761196
PMCID:
PMC3477504
DOI:
10.1002/cm.21045
[Indexed for MEDLINE]
Free PMC Article

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