Format

Send to

Choose Destination
See comment in PubMed Commons below
Brain Inj. 2012;26(13-14):1731-6. doi: 10.3109/02699052.2012.698364. Epub 2012 Jul 3.

Cerebral atrophy is associated with development of chronic subdural haematoma.

Author information

1
Department of Neurosurgery, New York University School of Medicine, New York, NY, USA.

Abstract

OBJECTIVE:

To test that cerebral atrophy is associated with increased risk for development of chronic subdural haematoma (cSDH), this study performed volumetric analysis of computed tomography (CT) brain scans from patients who were diagnosed with cSDH on subsequent CT scans and their age-matched controls.

METHODS:

Volumetric analysis was performed on CT scans acquired a mean of 209 days prior to cSDH diagnosis in 19 patients. Cerebral atrophy present on these scans was then compared to 76 age-matched control patients randomly selected from cSDH-free subjects.

RESULTS:

There was a higher degree of atrophy in cSDH patients (n = 19, 14.3% ± 5.4%) than in age-matched control patients (n = 76, 11.9% ± 5.5%; p = 0.044). Logistical regression demonstrated that atrophy was found to be a significant predictor of cSDH at all ages (OR = 1.11, 95% CI = [1.01, 1.23], p = 0.05). For younger subjects ≤65 years of age (n = 50), atrophy was an even stronger predictor of cSDH (OR = 1.17, 95% CI = [1.02, 1.34], p = 0.026).

CONCLUSIONS:

Cerebral atrophy is associated with the development of cSDH and this association is greater in patients ≤65 years of age.

PMID:
22759238
PMCID:
PMC5189658
DOI:
10.3109/02699052.2012.698364
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Taylor & Francis Icon for PubMed Central
    Loading ...
    Support Center