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Prenat Diagn. 1990 Oct;10(10):643-51.

Diagnosis and significance of cystic hygroma in the first trimester.

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Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, CT.


Thirty cases of cervical cystic hygroma were diagnosed in the first trimester of pregnancy. Karyotype analysis was available in 29 (97 per cent). Fifteen (52 per cent) had a chromosomal abnormality. The ultrasound appearance was described as posterior cervical, lateral cervical, or cervical hygroma with hydrops. Of the 14 euploid embryos, six were electively aborted, two are undelivered, and six have been delivered as phenotypically normal infants. In cases in which the chromosomes were normal and the pregnancy continued, all lesions resolved by 18 weeks.

[Indexed for MEDLINE]

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