Sexual dysfunction following radical prostatectomy

J Androl. 2012 Nov-Dec;33(6):1143-54. doi: 10.2164/jandrol.112.016790. Epub 2012 Jun 28.

Abstract

Prostate cancer is the most common solid cancer in men and the second leading cause of cancer death in men. A favored treatment option for organ-confined prostate cancer in a middle-aged healthy man is radical prostatectomy (RP). Despite advances in techniques for RP, there remain concerns among physicians and patients alike on its adverse effects on sexual function. Although post-RP erectile dysfunction has been extensively studied, little attention has been focused on the other domains of sexual function, namely loss of libido, ejaculatory dysfunction, orgasmic dysfunction, penile shortening, and Peyronie disease. The aim of this review is to discuss the most recent literature regarding post-RP sexual dysfunctions.

Publication types

  • Review

MeSH terms

  • Alprostadil / therapeutic use
  • Animals
  • Erectile Dysfunction / etiology
  • Humans
  • Libido
  • Male
  • Middle Aged
  • Penile Induration / etiology
  • Penis / drug effects
  • Penis / physiopathology
  • Piperazines / therapeutic use
  • Prostatectomy / adverse effects*
  • Prostatic Neoplasms / surgery*
  • Purines / therapeutic use
  • Quality of Life
  • Sexual Dysfunctions, Psychological / drug therapy
  • Sexual Dysfunctions, Psychological / etiology*
  • Sildenafil Citrate
  • Sulfones / therapeutic use

Substances

  • Piperazines
  • Purines
  • Sulfones
  • Sildenafil Citrate
  • Alprostadil