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Breast Care (Basel). 2012 Apr;7(2):147-149. Epub 2012 Apr 24.

Diagnosis and Management of Multiple Carcinosarcoma of the Breast in a Young Chinese Patient.

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Department of Surgical Oncology, the Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.



Carcinosarcoma is an exceptionally rare and poorly differentiated kind of breast neoplasm with only few published reports in the literature.


We report a case of breast carcinosarcoma in a 26-year-old Chinese female patient, presenting as multiple lumps in a single breast. A nipple-sparing modified radical mastectomy was performed. The patient is now in her 7th postoperative month and disease-free.


Carcinosarcoma is challenging to diagnose preoperatively, even with core needle biopsy histopathology. Modified radical mastectomy is an efficient and practical operative treatment. Application of adjuvant therapy should be based on the proportion of carcinomatous component of the lesion in pathological test. Careful periodic follow-up after the initial treatment is strongly recommended.

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