Female sexual dysfunction in type 2 diabetes: a case control study

Med Princ Pract. 2012;21(6):554-9. doi: 10.1159/000339118. Epub 2012 Jun 27.

Abstract

Objective: This study was designed to assess sexual dysfunction in women suffering from type 2 diabetes mellitus.

Subjects and methods: Forty-five type 2 diabetic, non-menopausal married women, aged 20-55 years, who were referred to Shahid Labbafinejad Clinics from March 2008 to June 2009 were included in this study. They were compared to 91 non-diabetic volunteers. Sexual function was evaluated by the sexual function questionnaire. Genitourinary examination was performed in all subjects. Blood sample tests were requested for fasting blood sugar, hemoglobin A(1c), 2-hour postprandial glucose and lipid profile measurements. Ophthalmologic and neurologic examinations (checking deep tendon reflexes) were done for cases.

Results: The mean age of cases and controls was 42.17± 5.91 and 34.96 ± 8.30 years, respectively (p < 0.001). The prevalence of a high probability of female sexual dysfunction in 6 domains including desire, arousal sensation, arousal lubrication, orgasm, pain and enjoyment was 71.1, 84.4, 55.6, 71.1, 8.9 and 66.7% in the diabetes mellitus women and 56.6, 67.0, 59.3, 57.1, 25.3 and 53.8% in the non-diabetic volunteers, respectively. Differences were statistically significant in the 3 domains of desire, arousal sensation and pain (p < 0.05). Deep tendon reflexes were normal in all and 12.5% showed diabetic retinopathy.

Conclusions: Sexual dysfunction in cases as well as in controls was high; however, further studies with a higher number of patients are needed to confirm the results.

MeSH terms

  • Adult
  • Case-Control Studies
  • Chi-Square Distribution
  • Diabetes Complications
  • Diabetes Mellitus, Type 2 / complications*
  • Female
  • Health Status Indicators
  • Humans
  • Iran / epidemiology
  • Middle Aged
  • Prevalence
  • Risk Factors
  • Sexual Dysfunction, Physiological / epidemiology*
  • Sexual Dysfunction, Physiological / etiology
  • Sexual Dysfunction, Physiological / psychology
  • Sexual Dysfunctions, Psychological / epidemiology
  • Sexual Dysfunctions, Psychological / etiology
  • Sexual Dysfunctions, Psychological / psychology
  • Surveys and Questionnaires
  • Young Adult