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J Clin Virol. 2012 Sep;55(1):62-6. doi: 10.1016/j.jcv.2012.05.014. Epub 2012 Jun 26.

Comparison of the QIAGEN artus HIV-1 QS-RGQ test with the Roche COBAS AmpliPrep/COBAS TaqMan HIV-1 test v2.0.

Author information

1
Department of Virology, Barts Health NHS Trust, London E1 2ES, UK.

Abstract

BACKGROUND:

Regular HIV-1 viral load monitoring is standard of care in the developed world for patients infected with HIV-1.

OBJECTIVES:

Here we report a comparative evaluation of the established Roche COBAS AmpliPrep/COBAS TaqMan HIV-1 v2.0 test (Roche Diagnostics Ltd, Burgess Hill, UK) and the new artus HIV-1 QS-RGQ test (QIAGEN Ltd, Crawley, UK).

STUDY DESIGN:

169 clinical EDTA-plasma samples were tested, all of known HIV-1 subtype.

RESULTS:

The mean overall log(10)c/ml difference was 0.10 (QIAGEN - Roche).

CONCLUSION:

The artus HIV-1 QS-RGQ test compared well with the Roche TaqMan HIV-1 v2.0 test, and Bland-Altman analysis showed good agreement between the two systems across a wide range of subtypes.

PMID:
22739101
DOI:
10.1016/j.jcv.2012.05.014
[Indexed for MEDLINE]

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