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J Clin Periodontol. 2012 Sep;39(9):824-33. doi: 10.1111/j.1600-051X.2012.01916.x. Epub 2012 Jun 26.

Tooth loss is associated with increased blood pressure in adults--a multidisciplinary population-based study.

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Oral Epidemiology and Dental Public Health Research Group, Post-Graduate Program in Public Health, Federal University of Santa Catarina, Florianópolis, Brazil.



To investigate whether tooth loss is associated with increased blood pressure among adults after controlling for socioeconomic, health, and lifestyle confounders. We also assessed the interactions between tooth loss and smoking status and tooth loss and age on systolic blood pressure (SBP).


A population-based cross-sectional study was carried out with 1720 adults from Florianópolis, Brazil. Data collection included blood pressure, anthropometric measures, and a questionnaire on socio-demographics, self-rated health, diabetes, self-reported number of natural teeth, and dental prosthesis. We used linear multivariable regression models for the association of blood pressure with tooth loss adjusting for potential confounders.


Edentulous subjects had a SBP 8.3 mmHg (95% CI 0.1; 16.7) higher than those with more than 10 teeth in both arches after adjustment for potential confounders. We found interaction between tooth loss and smoking status. Moderate/heavy smokers were associated with considerably higher SBP than light, former or non-smokers among edentulous and also partly among dentate with less than 10 teeth in at least one arch, but there was no real association between smoking and SBP among those with 10 or more teeth in both arches.


Total tooth loss is associated with increased levels of SBP in this adult population.

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