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Int J Eat Disord. 2012 Dec;45(8):970-6. doi: 10.1002/eat.22037. Epub 2012 Jun 26.

Psychotropic medication use in anorexia nervosa between 1997 and 2009.

Author information

1
Neuroendocrine Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

Abstract

OBJECTIVE:

Despite a lack of data demonstrating benefit, psychotropic medications are frequently prescribed for patients with anorexia nervosa.

METHOD:

We studied 525 women (18-54 years of age) with anorexia nervosa who presented to the Clinical Research Center at the Massachusetts General Hospital between January 1997 and December 2009. For this analysis, participants were a priori divided into two groups based on date of presentation (Group I: participants presenting between 1997 and 2002; Group II: participants presenting between 2003 and 2009).

RESULTS:

Overall, 53% of participants reported current use of any psychotropic medication; 48.4% reported use of an antidepressant and 13% reported use of an antipsychotic. Twice as many participants in Group II (18.5%) reported using atypical antipsychotics as compared to Group I (8.9%) (p = 0.002).

DISCUSSION:

A majority of participants with anorexia nervosa report using psychotropic medications despite lack of data supporting their efficacy. These data are concerning given the known adverse effects of these medications.

PMID:
22733643
PMCID:
PMC3726215
DOI:
10.1002/eat.22037
[Indexed for MEDLINE]
Free PMC Article

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