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Chem Soc Rev. 2012 Aug 21;41(16):5484-9. doi: 10.1039/c2cs35073d. Epub 2012 Jun 25.

Chemical evolution from simple inorganic compounds to chiral peptides.

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1
Institute of Analytical Chemistry and Radiochemistry, University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria. Thomas.Jakschitz@uibk.ac.at

Abstract

Numerous experiments performed in the past 50 years have strongly changed ideas of how life could have emerged on the primitive Earth. This review deals with the synthesis of biomolecule precursors under the conditions prevailing on the primordial Earth, and describes possible scenarios for their combination and elongation to form peptides and proteins. Furthermore it proposes different answers to one of the big secrets of nature: why DNA-coded biohomochiral life emerged using amino acids in their l-form?

PMID:
22733315
DOI:
10.1039/c2cs35073d
[Indexed for MEDLINE]
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