Format

Send to

Choose Destination
Angew Chem Int Ed Engl. 2012 Jul 9;51(28):6824-6. doi: 10.1002/anie.201203059. Epub 2012 Jun 21.

Resveratrol still has something to say about aging!

Author information

1
Univ. Bordeaux, Institut des Sciences Moléculaires & Institut Européen de Chimie et Biologie, Pessac, France. s.quideau@iecb.u-bordeaux.fr

Abstract

A votre Santé! The mechanism by which resveratrol, a hydroxystilbenoid polyphenol found in grapes and present in wine, exerts antiaging metabolic benefits has been uncovered. Chung and co-workers have found that it works by inhibiting cAMP phosphodiesterases, thus triggering a signaling cascade that leads to the possible activation of the mammalian enzyme sirtuin 1.

PMID:
22730253
DOI:
10.1002/anie.201203059
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center