Format

Send to

Choose Destination
Cell. 2012 Jun 22;149(7):1424-5. doi: 10.1016/j.cell.2012.06.004.

Membrane protein structure predictions for exploration.

Author information

1
Howard Hughes Medical Institute, Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX 75390-9050, USA. grishin@chop.swmed.edu

Abstract

A daring experiment is performed. Using sequence alignments to predict contacts between residues in protein spatial structures, Hopf et al. are publishing untested de novo structure models for 11 transmembrane protein families. Will their models stand the test of time and hold up to experimentation? The prospects are excellent.

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center