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Laterality. 2013;18(2):251-61. doi: 10.1080/1357650X.2012.660164. Epub 2012 Jun 21.

Non-replication of an association of Apolipoprotein E2 with sinistrality.

Author information

1
Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR, USA. psy391@gmail.com

Abstract

A recent report found that left-handed adolescents were more than three times more likely to have an Apolipoprotein (APOE) ϵ2 allele. This study was unable to replicate this association in young adults (N=166). A meta-analysis of nine other datasets (N=360 to 7559, Power > 0.999) including that of National Alzheimer's Coordinating Center also failed to find an over-representation of ϵ2 among left-handers indicating that this earlier outcome was most likely a statistical artefact.

PMID:
22721421
PMCID:
PMC3770935
DOI:
10.1080/1357650X.2012.660164
[Indexed for MEDLINE]
Free PMC Article

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