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Oncoimmunology. 2012 Jan 1;1(1):123-125.

Cytotoxic T lymphocytes: Sniping cancer stem cells.

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1
Department of Pathology; Sapporo Medical University School of Medicine; Sapporo, Japan.

Abstract

Cancer stem cells (CSCs)/cancer-initiating cells (CICs) are characterized as a small population of cancer cells that have high tumor-initiating ability. CSCs/CICs are resistant to several cancer therapies, and eradication of CSCs/CICs is essential to cure cancer. How can we eradicate CSCs/CICs? Cytotoxic T lymphocytes (CTLs) might be a promising answer.

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